Hey, I’m Nellie.
-And I’m Rens. And welcome…
-In our Drugslab. I’m a bit dizzy. It tickles a little. Stop, stop. We already have
over 300,000 subscribers. We’re super glad we can inform you about
different kinds of drugs every week… and show you what they do
to our body. If you want to see a drug,
leave a comment. Jonatan Rez, Philip Andersson
and SubWoofer did so too. They’re very curious about OxyContin. This is the painkiller OxyContin. It’s a small, yellowish pill. The pill
we have contains 40 mg oxycodone. OxyContin is a strong painkiller
that blocks pain signals to the brain. People with chronic pain
benefit a lot from this medicine. But it’s extremely addictive. In the US there was a steep rise
in people addicted to OxyContin. Doctors first said it wasn’t addictive
at all, but then it turned out that it was. It’s an opiate,
so it’s made from the opium plant… just like morphine and heroin. So when you’re addicted
and don’t get it prescribed anymore… the temptation to switch to heroin
lurks around the corner. Never combine OxyContin with other
tranquilizers such as GHB or alcohol. That can make you very sleepy… and increases the risk of a blackout
and of respiratory arrest. You must also not combine it
with grapefruit juice. That may sound funny,
but it can be dangerous. It’s time for paper, rock, scissors.
The loser will take it. Yes?
Paper, rock, scissors. Yes, you. I won.
-Yeah-yeah. I’m going to put on my belt.
-Excellent. OxyContin anaesthetizes, but it can also
make you confused, cause mood swings. It can also cause constipation, it can
make you blush, give you a dry mouth. Delusions, an itchy nose, and it can make
you have very strange and intense dreams. We’re going to do a few tests beforehand.
I’ll start with the pain stimulus. Come here with your arm.
Give it a score between 0 and 10. Yes, enough.
-And? I’m sorry.
-An 8 plus. An 8.
-Yes. Now your reactive power. You have
to tap as soon as you see the circle. 248 milliseconds.
-Insanely fast, right? 248. I have clothes pegs here, which I’m
going to attach to your face and hands. Let’s see how many you can handle. Let me first put one here. Stop. This one has to go.
-Yes, is that enough? Okay. One, two, three, sorry, four… Nine, ten, eleven.
Twelve clothes pegs. If you get this on prescription,
be careful and read the instructions. Don’t take more
than the prescription says. If you have no tolerance to opiates,
40 mg is actually a very heavy dose. So for you it’s smart to start with 10. Doctors prescribe it against pain,
but people also use it to get high. It takes 30 minutes to an hour
to take effect. The narcotic effects last 2-4 hours,
and the after-effects last up to 6 hours. It’s different from that cactus, isn’t it?
-Yes. A lot easier, isn’t it?
-Yes. And now we wait. I’m a bit dizzy. A little… I feel like
I have to breathe in and out deeply. I’m a bit nauseous.
Here in my stomach. It’s as if my body
has to acclimatize a little. I do have this vague feeling
that there’s something… It’s a bit vague.
I can’t really put my finger on it. But you feel you’re under the influence.
-Yes, a little. I feel a little anaesthetized. But you don’t feel twitches
or strange sensations in your body? No. Your pupils are small. Yes, very small.
-That’s odd, usually they’re very large. Now they’re little pinpricks. Your temperature went up as well.
-Yes. Let me see…
Yes, I’m actually perspiring. It lowers the blood pressure, of course.
That also explains the dizziness. If your blood pressure drops, you tend
to get dizzy. And I notice I’m a bit dizzy. I feel I’m becoming more quiet.
-Yes, you seem very calm. Can you imagine that if you have problems,
they seem less bad now… because they get suppressed?
-Yes. Yes, if you’re calm in your mind,
you don’t tend to worry so much. With MDMA you immediately
feel something very intense. And this is such a minor change. But I also noticed that with cocaine.
That’s why it’s so addictive. Basically you can just continue working.
People don’t notice. This is the same. If you’re very restless
and suddenly you experience this calm… It’s not really intense, but it may be
just that small step you need to relax. And that is really bloody dangerous. My temperature keeps rising,
but I actually feel kind of shivery. That’s odd. My body is restless,
but my mind is relaxed. Do you feel more euphoric
than before you took it? I think so, a little bit.
-That’s possible. Many people say it makes them
a little euphoric. I already felt cheerful,
but now that feeling is a little stronger. It makes you very sleepy and sluggish.
That’s why it’s not smart to drive a car… or to operate a machine. I do have a really dry mouth. I can keep
drinking water. One sip and it’s dry again. Shall we do this one for once?
-Yes. Normally I can’t stand it.
It makes me go: Good idea. Well…
-It’s not that nice at all now. No? Usually you fly off your chair. It’s much less now. Funny, you really feel much less.
-Yes. We’re going to do the tests. Stop it. That went really well.
-You did it really hard. Yes, I really held on to you. Still an 8.
-Still an 8? I think he furtively pinched harder now.
-Then the reaction test. 286.
-286. Not as good. On to the last test, the clothes pegs.
-Oh no. Sorry, I know, this isn’t nice. Oh, stop.
-Enough? You now had 1, 2, 3, 4, 5, 6, 7, 8, 9, 10.
Your skin is very sensitive, of course. You really need a lot to anaesthetize it. It mainly anaesthetizes inside
and your muscles… so let’s see what happens
when I pinch your shoulder. Wow, I’m pinching hard.
Doesn’t this hurt? Yes, not… Now it does.
-I was pinching really hard. If people black out, that’s what to do
to make them come to again. That’s how painful it is. Can I do it to you as well?
-Go ahead. Oh, stop, stop. Many people think medicines are safer than
drugs you use at a party, for instance. But abusing medicines does carry risks,
one of which is addiction. And if you’re addicted, don’t stop cold
turkey but get professional supervision. Do you still feel anything?
-Yes, I still feel calm. Your temperature has gone up to 37.5. This was Drugslab for this week. If you’re
curious about a drug, let us know. And we’re also interested
in other stories about drugs. And if you’ve already subscribed:
I love you. If you haven’t: go and do so. Also let your friends subscribe
and give it your thumbs-up. And maybe your grandpa will enjoy it too.
-Sure thing. Bye. When I came home I really felt awful.
Nausea, headache, fucking tired. I slept very restlessly
and dreamed a lot. I’ll see you again next time.